Quantification of the Synthetic Phenolic Antioxidant Cyanox 1790 in Bottled Water with SPE-HPLC/MS/MS and Determination of the Impact of the Use of Recycled Packaging on Its Generation

Abstract

One route of exposure to SPAs is through bottled water since the polymers used to make plastic bottles contain these SPAs, which migrate from the plastic to the water. Solid-phase extraction (SPE), HPLC-MS, FTIR, and DSC are used to identify and quantify these SPAs in water. Interday measurements of cyanox 1790 in water with HPLC showed RSD, error, and R2 lower than 3.78, 9.3,and 0.99995, respectively. For intraday measurements of cyanox 1790 in water, the RSD, error, and R2 were less than 4.1, 11.2, and 0.99995, respectively. Concentrations of Cyanox 1790 in water from non-recycled bottles ranged from 0.01 ± 0.0004 to 4.15 ± 0. 14 ppm, while the levels of cyanox 1790 in water in recycled bottles ranged between 0.01 ± 0.0005 and 11.27 ± 0.12 ppm. In the tests carried out, an increase in the migration of Cyanox 1790 from plastic bottles to water was identified, since the ppm of Cyanox increased in the water as the days of storage increased at 40 ◦C.