• A Hooke's law-based approach to protein folding rate 

      Ruiz-Blanco Y.B.; Marrero-Ponce Y.; Prieto P.J.; Salgado J.; García Y.; Sotomayor-Torres C.M. (Academic Press, 2015)
      Kinetics is a key aspect of the renowned protein folding problem. Here, we propose a comprehensive approach to folding kinetics where a polypeptide chain is assumed to behave as an elastic material described by the ...
    • A machine learning model for emotion recognition from physiological signals 

      Domínguez-Jiménez, J.A.; Campo Landines, Kiara; Martínez-Santos, J.C.; De la Hoz Domínguez, Enrique José; Contreras Ortiz, Sonia Helena (Elsevier Ltd, 2020)
      Emotions are affective states related to physiological responses. This study proposes a model for recognition of three emotions: amusement, sadness, and neutral from physiological signals with the purpose of developing a ...
    • Anatomical Pathology of the Umbilical Cord and Its Maternal and Fetal Clinical Associations in 434 Newborns 

      Olaya-C M.; Gil F.; Salcedo J.D.; Salazar A.J.; Silva J.L.; Bernal J.E. (SAGE Publications Ltd, 2018)
      Introduction: Umbilical cord (UC) abnormalities and their clinical relations in 434 newborns were analyzed. We had previously reported on clinical associations of long and short UCs with any kind of malformation. This study ...
    • Effectiveness of a visual noise warning system on noise levels in a surgical ICU: A quality improvement programme 

      Guisasola-Rabes M.; Solà-Enriquez B.; Vélez-Pereira A.M.; De Nadal M. (Lippincott Williams and Wilkins, 2019)
      BACKGROUNDThe effects of noise are harmful to patients in the ICU environment, and the latter are particularly noisy places. High noise levels seem to be a factor in sleep disturbance, which can, in turn, result in increased ...
    • Features of dengue and chikungunya infections of colombian children under 24 months of age admitted to the emergency department 

      Paternina-Caicedo A.; De la Hoz-Restrepo F.; Díaz-Quijano F.; Caicedo-Torres W.; Badillo-Viloria M.A.; Bula-Anichiarico D.; Alvis-Guzmán N.; Mattar S.; Constenla D.; Pinzón-Redondo H. (Oxford University Press, 2018)
      We aimed to assess clinical and laboratory differences between dengue and chikungunya in children <24 months of age in a comparative study. We collected retrospective clinical and laboratory data confirmed by NS1/IgM for ...
    • In silico drug repurposing for the identification of potential candidate molecules against arboviruses infection 

      Montes-Grajales D.; Puerta-Guardo H.; Espinosa D.A.; Harris E.; Caicedo-Torres W.; Olivero-Verbel J.; Martínez-Romero E. (Elsevier B.V., 2020)
      Arboviral diseases caused by dengue (DENV), Zika (ZIKV) and chikungunya (CHIKV) viruses represent a major public health problem worldwide, especially in tropical areas where millions of infections occur every year. The aim ...
    • ISeeU: Visually interpretable deep learning for mortality prediction inside the ICU 

      Caicedo-Torres W.; Gutierrez J. (Academic Press Inc., 2019)
      To improve the performance of Intensive Care Units (ICUs), the field of bio-statistics has developed scores which try to predict the likelihood of negative outcomes. These help evaluate the effectiveness of treatments and ...
    • Male facial anthropometry and attractiveness 

      Soler C.; Kekäläinen J.; Núñez M.; Sancho M.; Núñez J.; Yaber Goenaga, Iván; Gutiérrez R. (2012)
      The symmetry and masculinity of the face are often considered important elements of male facial attractiveness. However, facial preferences are rarely studied on natural faces. We studied the effect of these traits and ...
    • Multi-output model with box-jenkins operators of quadratic indices for prediction of malaria and cancer inhibitors targeting ubiquitin-proteasome pathway (UPP) proteins 

      Casañola-Martín G.M.; Le-Thi-Thu H.; Pérez-Giménez F.; Marrero-Ponce Y.; Merino-Sanjuán M.; Abad C.; González-Díaz H. (Bentham Science Publishers B.V., 2016)
      The ubiquitin-proteasome pathway (UPP) is the primary degradation system of short-lived regulatory proteins. Cellular processes such as the cell cycle, signal transduction, gene expression, DNA repair and apoptosis are ...
    • Multi-server approach for high-throughput molecular descriptors calculation based on multi-linear algebraic maps 

      García-Jacas C.R.; Aguilera-Mendoza, L.; González-Pérez R.; Marrero-Ponce Y.; Acevedo-Martínez L.; Barigye S.J.; Avdeenko T. (Wiley-VCH Verlag, 2015)
      The present report introduces a novel module of the QuBiLS-MIDAS software for the distributed computation of the 3D Multi-Linear algebraic molecular indices. The main motivation for developing this module is to deal with ...
    • Novel 3D bio-macromolecular bilinear descriptors for protein science: Predicting protein structural classes 

      Marrero-Ponce Y.; Contreras-Torres E.; García-Jacas C.R.; Barigye S.J.; Cubillán, Néstor; Alvarado Y.J. (Academic Press, 2015)
      In the present study, we introduce novel 3D protein descriptors based on the bilinear algebraic form in the ℝn space on the coulombic matrix. For the calculation of these descriptors, macromolecular vectors belonging to ...
    • Optimum search strategies or novel 3D molecular descriptors: Is there a stalemate? 

      Marrero-Ponce Y.; García-Jacas C.R.; Barigye S.J.; Valdés-Martiní J.R.; Rivera-Borroto O.M.; Pino-Urias R.W.; Cubillán, Néstor; Alvarado Y.J.; Le-Thi-Thu H. (Bentham Science Publishers B.V., 2015)
      The present manuscript describes a novel 3D-QSAR alignment free method (QuBiLS-MIDAS Duplex) based on algebraic bilinear, quadratic and linear forms on the kth two-tuple spatial-(dis)similarity matrix. Generalization schemes ...
    • Pixel-wise rational model for a structured light system 

      Vargas, Raúl; Romero, Lenny A; Zhang, Song; Marrugo, Andrés G. (Cartagena de Indias, 2023-05-15)
      This Letter presents a novel structured light system model that effectively considers local lens distortion by pixel-wise rational functions. We leverage the stereo method for initial calibration and then estimate the ...
    • Restoration of retinal images with space-variant blur 

      Marrugo A.G.; Millán M.S.; Šorel M.; Šroubek F. (2014)
      Retinal images are essential clinical resources for the diagnosis of retinopathy and many other ocular diseases. Because of improper acquisition conditions or inherent optical aberrations in the eye, the images are often ...
    • Robust automated reading of the skin prick test via 3D imaging and parametric surface fitting 

      Pineda J.; Vargas R.; Romero L.A.; Marrugo J.; Meneses J.; Marrugo A.G. (Public Library of Science, 2019)
      The conventional reading of the skin prick test (SPT) for diagnosing allergies is prone to inter- and intra-observer variations. Drawing the contours of the skin wheals from the SPT and scanning them for computer processing ...
    • Role of VEGF in the differential growth between the fetal and placental ends of the umbilical cord 

      Olaya-C M.; Michael F.; Fabian G.; Luis Silva J.; Bernal J.E.; Garzon A.L. (IOS Press, 2019)
      INTRODUCTION: The umbilical cord (UC) is a vital structure; its alterations affect the newborn and neurological impact can be permanent. Paradoxically, factors that determine it remain unknown. We explore the differential ...
    • Towards better BBB passage prediction using an extensive and curated data set 

      Brito-Sánchez Y.; Marrero-Ponce Y.; Barigye S.J.; Yaber Goenaga, Iván; Morell Pérez C.; Le-Thi-Thu H.; Cherkasov A. (Wiley-VCH Verlag, 2015)
      In the present report, the challenging task of drug delivery across the blood-brain barrier (BBB) is addressed via a computational approach. The BBB passage was modeled using classification and regression schemes on a novel ...
    • Umbilical cord and preeclampsia 

      Olaya-C M.; Salcedo-Betancourt J.; Galvis S.H.; Ortiz A.M.; Gutierrezb S.; Bernal J.E. (IOS Press, 2016)
      Preeclampsia is associated with abnormalities in the umbilical cord in several ways: morphological, biochemical and functional. Alteration in blood vessels of the placenta, decidua and circulatory system of the fetus might ...
    • Vehicular road influence areas 

      Huertas M.E.; Huertas, J.I.; Valencia A. (Elsevier Ltd, 2017)
      Vehicle operation over paved and unpaved roads is an emission source that significantly contributes to air pollution. Emissions are derived from vehicle exhaust pipes and re-suspension of particulate matter generated by ...
    • Volatile organic compounds in the atmosphere of Mexico City 

      Garzón, J.P.; Huertas, J.I.; Magaña, M.; Huertas, M.E.; Cárdenas, B.; Watanabe, T.; Maeda, T.; Wakamatsu, S.; Blanco, S. (Elsevier Ltd, 2015)
      The Mexico City Metropolitan Area (MCMA) is one of the most polluted megacities in North America. Therefore, it is an excellent benchmark city to understand atmospheric chemistry and to implement pilot countermeasures. Air ...

      Universidad Tecnológica de Bolívar - 2017 Institución de Educación Superior sujeta a inspección y vigilancia por el Ministerio de Educación Nacional. Resolución No 961 del 26 de octubre de 1970 a través de la cual la Gobernación de Bolívar otorga la Personería Jurídica a la Universidad Tecnológica de Bolívar.