2020-03-262020-03-262018Pediatric and Developmental Pathology; Vol. 21, Núm. 5; pp. 467-47410935266https://hdl.handle.net/20.500.12585/8870Introduction: Umbilical cord (UC) abnormalities and their clinical relations in 434 newborns were analyzed. We had previously reported on clinical associations of long and short UCs with any kind of malformation. This study focuses on other UC features (insertion, vessels, entanglements, coiling, and knots) and their associations with clinical characteristics and neonatal prognosis. Methods: An observational analytic study was performed on placentas from consecutive deliveries. Ordered logistic regression with bivariate and multivariate analysis was performed to evaluate the relationship between variables of interest concerning UC abnormalities. Results: A total of 434 placentas made up the study. UC abnormalities were abnormal insertion, 82 (18.86%); coiling (hypo and hypercoiled), 177 (40.78%); single umbilical artery (SUA), 4 (0.92%); entanglements, 8 (1.84%); true knots, 3 (0.69%); webs in UC base, 9 (2.07%); and right twist, 68 (15.67%). After analyzing maternal and fetal complications during pregnancy, multivariate analysis confirmed the recognized association between malformations and SUA and male gender; further confirmation was also made between hypertensive disorders of pregnancy and true knots. Discussion: UC abnormalities associated with undesirable outcomes are varied and should be recognized and described. Clinical factors associated with anatomical UC abnormalities are not completely understood and justify forthcoming studies. © 2018, Society for Pediatric Pathology All rights reserved.Recurso electrónicoapplication/pdfenghttp://creativecommons.org/licenses/by-nc-nd/4.0/info:eu-repo/semantics/article10.1177/1093526618758204Coiling indexCord accidentPlacentaSingle umbilical arteryStillbirthUmbilical cordUbiquitinAntemortem skin biopsyArchicortexArticleAspiration pneumoniaAutopsyBrain ventricle dilatationBronchiolitisCase reportCaudate nucleusCause of deathCell lossCentral nervous systemCerebellum atrophyChildClarke columnClinical articleConvulsionCopy number variationCorpus striatumCortical gliosisDegenerative diseaseDentate nucleusDevelopmental disorderDyskinesiaElectron microscopyFemaleFeverGray matterHereditary motor sensory neuropathyHistologyHospital admissionHumanHuman cellHuman tissueMicroarray analysisMuscle atrophyMuscle biopsyNeocortexNuronal intranuclear inclusion diseaseNuclear magnetic resonance imagingPathogenesisPathologyPreschool childPriority journalPurkinje cellRecurrent diseaseSeizureSkin biopsySubstantia nigraWalking difficultyAdolescentAdultMaleNewbornPathologyPlacentaPregnancyStillbirthUmbilical cordYoung AdultAdolescentAdultFemaleHumansInfant, NewbornMalePlacentaPregnancyStillbirthUmbilical CordYoung Adultinfo:eu-repo/semantics/restrictedAccessAtribución-NoComercial 4.0 InternacionalUniversidad Tecnológica de BolívarRepositorio UTB56461296300130074078005720069553257200700975740302345353871077300